Tianyu's Blog

Thoughts, research, and insights


Can a virtual cell predict a pathway it has never seen switch on?

A pilot on 24,562 human blood cells asks what expression data, mechanistic knowledge and a handful of experiments each contribute to predicting an interferon response a model has never observed.

40 min read   ·   2026

Why metabolic maps turn into hairballs, and how to draw one that doesn't

A force-directed layout of a metabolic model collapses onto ATP and water. Three ideas from MetaCarto that get a curator-style map out of the same network instead.

7 min read   ·   2026

The Generalist and the Specialist: Understanding the NVIDIA GPU and Google TPU Architectures

Compare the NVIDIA GPU and Google TPU

6 min read   ·   2025

The Beginner's Guide to Understanding NVIDIA GPUs

how GPU works to speed up your code

8 min read   ·   2025

The Race for the Digital Twin: State of Whole-Cell Modeling in 2025

brief overview of current states of whole-cell modeling/virtual cell

9 min read   ·   2025